Endocrine Abstracts

Introduction: Worldwide, diabetes is a common metabolic disorder that creates many complications. Nowadays a mobile-based application could be included in the therapeutic approaches of self-management.Aim: This study presents the development of a mobile application named ‘Diabetes 2 Learn’ for people with type 2 diabetes inside the Greek population.Methods: Google Play and App Store were examined for their apps on diabete...

Pheochromocytoma is a rare tumor made up of chromaffin cells from the adrenal medulla that secrete catecholamines. It can occur at any age, with a peak incidence between the fourth and fifth decade of life, and only 10% of cases occur in children. The majority of cases are sporadic and approximately 10% are malignant. The existence of familial syndrome, multiple or extra adrenal tumors is more common at younger ages. The clinic is very variable, and hypertension (HTA) is the m...

Introduction: Primary lymphoma of the thyroid (PTL) is a rare cause of malignancy, accounting for 5% of thyroid malignancies, with an annual estimated incidence of 2 per 1 million. Women are more commonly affected than men (2–8:1). Patients typically present in the sixth or seventh decade of life. Most thyroid lymphomas are non-Hodgkin’s lymphomas (NHLs) of B-cell origin. Patients with Hashimoto’s thyroiditis are at greater risk for developing PTL. Treatment and...

Abstract: Cushing’s disease (CD) is the heavy disease of the hypothalamic–pituitary–adrenal axis. The cause of the disease is pituitary adenoma (corticotropinoma). Hypersecretion of ACTH by a pituitary adenoma leads to increased secretion of cortisol by the adrenal cortex and the development of total endogenous hypercortisolism. The gold standard treatment for this disease is surgical removal of corticotropinoma. However, adenomectomy is not effective in all cas...

Bulgaria is also among the countries with national data on the prevalence of Diabetes published in the Diabetes Atlas of the International Diabetes Federation’2019, but did not provide data on the incidence of Hyperglycemia in pregnant Bulgarian women.Purpose: The Bulgarian Society of Endocrinology organized and conducted screening for Hyperglycemia in pregnant women in 2019.Material and Methods: 547 pregnant women from 10 re...

In Bulgaria there are epidemiological data for the population of 20–80 years for the frequency of thyroid dysfunction – 6.3% hypothyroidism and 3.7% hyperthyroidism (Bulgarian Society of Endocrinology, 2012). So far, there is no national data on the incidence of thyroid disorders in pregnant women, which is a major lack of the health care system and the purpose of this study is to fill this gap.Material and Methods: We studied 547 pregnant Bu...

Background: Intravenous bisphosphonates treatment brings real benefits to patients with bone metastases. Unfortunately, this treatment sometimes has a difficult to treat complication, often disabling for the patients – the osteonecrosis of the jaws. A new approach in the management of this complication is the use of platelet rich plasma (PRP).Patients and methods: Five patients aged between 62 and 72 years old (three men and two women) were included...

Introduction: Long term remission of CD is achieved in 65–83% after neurosurgery, while the remaining cases have recurrence or continued tumor growth. This paper deals with the problem of CD prognostic factors after neurosurgery.Design: ACTH and cortisol blood levels, free cortisol in daily urine, MRI, histology (hemotaxiline–eosine staining) and immunohistochemistry (with antibodies to the pituitary tropic hormones, Ki-67, CD31 and VEGF) of th...

Nissen’s meta-analysis concluded that the use of Rosiglitazone (RSG) was associated with a significant increase in the risk of myocardial infarction. However, none of the analyzed studies took into account the cardiovascular events as primary outcomes, neither were controlled by cardiovascular risk factors.Objectives: 1. To know if there is an association between RSG myocardial infarction OR and the magnitude of the difference in baseline serum lipi...

Objective: Acromegaly is frequently associated with thyroid diseases. In this study we evaluated the incidence, morphology of the thyroid and the influence of surgery, iradiation and medical therapy used in acromegaly on thyroid function.Methods: We evaluated 20 patients diagnosed with acromegaly using thyroid ultrasonography and measurement of IGF1, GH, TSH, free T4. 65% of the patients had active disease and were under medical therapy.<p class="abs...